2012IOSR Journal of Pharmacy (IOSRPHR)Open access

Prevalence of microalbuminuria among sudanese type 2 diabetic patients at elmusbah center at ombadda - omdurman

Fayza A. Rahamtalla

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Abstract

Microalbuminuria is persistent albumin excretion between 30 and 300 mg/day, in patients with diabetes it is usually indicative of diabetic nephropathy which is most common cause of end stage renal disease, it is also associated with cardiovascular disease. Early detection of microalbuminuria and early control of diabetes retards the development of structural changes in early diabetic nephropathy. The main objective was to determine the prevalence of microalbuminuria on urine samples of Sudanese type 2 diabetic patients (non-insulin-dependent) which is expressed by Albumin creatinine ratio (ACR). Across-sectional hospital based study was carried out in Elmusbah Medical Center, from November 2008 to March 2009, fifty eight of type 2 diabetic patients studied included 29 females (aged 35 -80 years) and 29 males (aged 43 -88 years). Urinary albumin concentration was measured by immunoturbodimetric assay. Microalbuminuria was diagnosed in 26 (44%) patients. The prevalence of microalbuminuria was 8.66% from total populations at risk (N=300).The risk factors associated with microalbuminuria were found to be age, duration of diabetes, systolic and diastolic blood pressure.

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Microalbuminuria is persistent albumin excretion between 30 and 300 mg/day, in patients with diabetes it is usually indicative of diabetic nephropathy which is most common cause of end stage renal disease, it is also associated with cardiovascular disease. Early detection of microalbuminuria and early control of diabetes retards the development of structural changes in early diabetic nephropathy. The main objective was to determine the prevalence of microalbuminuria on urine samples of Sudanese type 2 diabetic patients (non-insulin-dependent) which is expressed by Albumin creatinine ratio (ACR). Across-sectional hospital based study was carried out in Elmusbah Medical Center, from November 2008 to March 2009, fifty eight of type 2 diabetic patients studied included 29 females (aged 35 -80 years) and 29 males (aged 43 -88 years). Urinary albumin concentration was measured by immunoturbodimetric assay. Microalbuminuria was diagnosed in 26 (44%) patients. The prevalence of microalbuminuria was 8.66% from total populations at risk (N=300).The risk factors associated with microalbuminuria were found to be age, duration of diabetes, systolic and diastolic blood pressure.

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Available abstract

Microalbuminuria is persistent albumin excretion between 30 and 300 mg/day, in patients with diabetes it is usually indicative of diabetic nephropathy which is most common cause of end stage renal disease, it is also associated with cardiovascular disease. Early detection of microalbuminuria and early control of diabetes retards the development of structural changes in early diabetic nephropathy. The main objective was to determine the prevalence of microalbuminuria on urine samples of Sudanese type 2 diabetic patients (non-insulin-dependent) which is expressed by Albumin creatinine ratio (ACR). Across-sectional hospital based study was carried out in Elmusbah Medical Center, from November 2008 to March 2009, fifty eight of type 2 diabetic patients studied included 29 females (aged 35 -80 years) and 29 males (aged 43 -88 years). Urinary albumin concentration was measured by immunoturbodimetric assay. Microalbuminuria was diagnosed in 26 (44%) patients. The prevalence of microalbuminuria was 8.66% from total populations at risk (N=300).The risk factors associated with microalbuminuria were found to be age, duration of diabetes, systolic and diastolic blood pressure.

Key concepts: Microalbuminuria, Center (category theory), Medicine, Gerontology, Endocrinology, Diabetes mellitus, Chemistry, Crystallography

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