2010•MD Conference ExpressRequires access

Results from the Penumbra Pivotal Stroke Trial Substudy

H. Q. Sinclair, Manoj Goyal

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Abstract

While the Penumbra Pivotal Stroke Trial demonstrated a recanalization rate of 81.6%, the rate of good clinical outcome, defined as a modified Rankin Scale (mRS) score =2, was relatively low (25%) [The Penumbra Pivotal Stroke Investigators. Stroke 2009]. This article discusses a subanalysis from the Penumbra Pivotal Stroke Trial, which evaluated whether a good initial noncontrast computed tomography and short time to recanalization predicted good clinical outcome in patients with acute ischemic stroke who were undergoing endovascular procedures.

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What this paper is about

While the Penumbra Pivotal Stroke Trial demonstrated a recanalization rate of 81.6%, the rate of good clinical outcome, defined as a modified Rankin Scale (mRS) score =2, was relatively low (25%) [The Penumbra Pivotal Stroke Investigators. Stroke 2009]. This article discusses a subanalysis from the Penumbra Pivotal Stroke Trial, which evaluated whether a good initial noncontrast computed tomography and short time to recanalization predicted good clinical outcome in patients with acute ischemic stroke who were undergoing endovascular procedures.

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Available abstract

While the Penumbra Pivotal Stroke Trial demonstrated a recanalization rate of 81.6%, the rate of good clinical outcome, defined as a modified Rankin Scale (mRS) score =2, was relatively low (25%) [The Penumbra Pivotal Stroke Investigators. Stroke 2009]. This article discusses a subanalysis from the Penumbra Pivotal Stroke Trial, which evaluated whether a good initial noncontrast computed tomography and short time to recanalization predicted good clinical outcome in patients with acute ischemic stroke who were undergoing endovascular procedures.

Key concepts: Penumbra, Modified Rankin Scale, Stroke (engine), Medicine, Clinical trial, Acute stroke, Radiology, Ischemic stroke

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