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1974•American Journal of Clinical PathologyRequires access

Cytochemical Staining with Oil Red O and forβ-Glucuronidase in the Diagnosis of Acute Leukemia

Michael Shaw, Virginia A. Klemp

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Abstract

Bone marrow aspirates from 30 cases of acute lymphocytic leukemia and 21 cases of acute non-lymphocytic leukemia were stained with oil red O and for β-glucuronidase. Globular oil red O positivity was seen more frequently in cases of acute lymphocytic leukemia, and granular oil red O positivity was observed in a greater percentage of cases of acute nonlymphocytic leukemia. Diffuse activity or blocks of β-glucuronidase positivity were found with equal frequencies in cases of acute lymphocytic leukemia and acute non-lymphocytic leukemia. Both stains are considered to be of little value in the classification of acute leukemia.

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What this paper is about

Bone marrow aspirates from 30 cases of acute lymphocytic leukemia and 21 cases of acute non-lymphocytic leukemia were stained with oil red O and for β-glucuronidase. Globular oil red O positivity was seen more frequently in cases of acute lymphocytic leukemia, and granular oil red O positivity was observed in a greater percentage of cases of acute nonlymphocytic leukemia. Diffuse activity or blocks of β-glucuronidase positivity were found with equal frequencies in cases of acute lymphocytic leukemia and acute non-lymphocytic leukemia. Both stains are considered to be of little value in the classification of acute leukemia.

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Available abstract

Bone marrow aspirates from 30 cases of acute lymphocytic leukemia and 21 cases of acute non-lymphocytic leukemia were stained with oil red O and for β-glucuronidase. Globular oil red O positivity was seen more frequently in cases of acute lymphocytic leukemia, and granular oil red O positivity was observed in a greater percentage of cases of acute nonlymphocytic leukemia. Diffuse activity or blocks of β-glucuronidase positivity were found with equal frequencies in cases of acute lymphocytic leukemia and acute non-lymphocytic leukemia. Both stains are considered to be of little value in the classification of acute leukemia.

Key concepts: Leukemia, Acute leukemia, Acute lymphocytic leukemia, Medicine, Pathology, Staining, Bone marrow, Chronic lymphocytic leukemia

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Cytochemical Staining with Oil Red O and forβ-Glucuronidase in the Diagnosis of Acute Leukemia — Research Paper | ScholarLens