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1997•European Journal of Gastroenterology & HepatologyRequires access

Endomysium: autoantigen in coeliac disease

Conleth Feighery, Alex Whelan, Donald G. Weir

Open publisher page 2 citations

Abstract

In coeliac disease, dietary exposure to gluten is associated with an autoimmune response to gastrointestinal antigens, including endomysium. Measurement of autoantibodies to endomysium is a highly specific and sensitive method of diagnosing coeliac disease. Analysis of the interaction between gluten and endomysium should provide a critical insight into the pathogenesis of this condition.

About this research paper

What this paper is about

In coeliac disease, dietary exposure to gluten is associated with an autoimmune response to gastrointestinal antigens, including endomysium. Measurement of autoantibodies to endomysium is a highly specific and sensitive method of diagnosing coeliac disease. Analysis of the interaction between gluten and endomysium should provide a critical insight into the pathogenesis of this condition.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

In coeliac disease, dietary exposure to gluten is associated with an autoimmune response to gastrointestinal antigens, including endomysium. Measurement of autoantibodies to endomysium is a highly specific and sensitive method of diagnosing coeliac disease. Analysis of the interaction between gluten and endomysium should provide a critical insight into the pathogenesis of this condition.

Key concepts: Endomysium, Coeliac disease, Medicine, Autoantibody, Immunopathology, Intestinal malabsorption, Gluten, Immunology

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