2006•Equilibrium ResearchOpen access

Regeneration of peripheral vestibular organs

Tsuyoshi Endo, Makoto Miura

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Abstract

Hair cell regeneration has been gradually shown to occur in the inner ears of mammals as well as birds; this has been particularly demonstrated in the vestibular system rather than the organ of Corti. Several new strategies including mitosis, self repair, transdifferentiation, and cell transplantation are being pursued to brimg about hair cell regeneration. This review discusses the field of inner ear hair cell regeneration in birds and mammals, and the relationship of inner ear regeneration to functional recovery.

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Hair cell regeneration has been gradually shown to occur in the inner ears of mammals as well as birds; this has been particularly demonstrated in the vestibular system rather than the organ of Corti. Several new strategies including mitosis, self repair, transdifferentiation, and cell transplantation are being pursued to brimg about hair cell regeneration. This review discusses the field of inner ear hair cell regeneration in birds and mammals, and the relationship of inner ear regeneration to functional recovery.

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Available abstract

Hair cell regeneration has been gradually shown to occur in the inner ears of mammals as well as birds; this has been particularly demonstrated in the vestibular system rather than the organ of Corti. Several new strategies including mitosis, self repair, transdifferentiation, and cell transplantation are being pursued to brimg about hair cell regeneration. This review discusses the field of inner ear hair cell regeneration in birds and mammals, and the relationship of inner ear regeneration to functional recovery.

Key concepts: Regeneration (biology), Hair cell, Transdifferentiation, Inner ear, Vestibular system, Organ of Corti, Biology, Anatomy

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