Rheumatic fever in children. A follow-up study with emphasis on cardiac sequelae.
Su‐chiung Chen, J.L. Donahoe, Leonard F. Fagan
Abstract
Open-access reader
Su‐chiung Chen, J.L. Donahoe, Leonard F. Fagan
Abstract
Open-access reader
Eighty-nine children with rheumatic fever between 1964 and 1978 were reviewed. There were 40 males and 49 females. The first attack occurred mostly between 6 and 12 years. Arthritis was present in 62.9%; carditis, 55.1%; chorea, 19.1%. Children were followed from 20 months to 15 years (mean 61 months). Seventeen developed current attacks (19.1%). On final examination, 40 had no heart disease, 30 had mild heart disease, 6 required valve surgery, 4 had died, and 9 had moderate heart disease but not operated. Chorea was present in 20 children. Six of them also had mitral insufficiency, 3 had recurrence after episode of chorea. Prompt diagnosis and treatment of streptococcal infection and penicillin prophylaxis need to be stressed. Service carditis on initial attack and recurrence predispose to the development of severe heart disease.
OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Eighty-nine children with rheumatic fever between 1964 and 1978 were reviewed. There were 40 males and 49 females. The first attack occurred mostly between 6 and 12 years. Arthritis was present in 62.9%; carditis, 55.1%; chorea, 19.1%. Children were followed from 20 months to 15 years (mean 61 months). Seventeen developed current attacks (19.1%). On final examination, 40 had no heart disease, 30 had mild heart disease, 6 required valve surgery, 4 had died, and 9 had moderate heart disease but not operated. Chorea was present in 20 children. Six of them also had mitral insufficiency, 3 had recurrence after episode of chorea. Prompt diagnosis and treatment of streptococcal infection and penicillin prophylaxis need to be stressed. Service carditis on initial attack and recurrence predispose to the development of severe heart disease.
Key concepts: Chorea, Carditis, Medicine, Rheumatic fever, Heart disease, Pediatrics, Surgery, Arthritis