Early Repolarization Syndrome - A New Electrical Disorder Associated With Sudden Cardiac Death -
Shinsuke Miyazaki, Ashok J. Shah, Michel Haı̈ssaguerre
Abstract
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Shinsuke Miyazaki, Ashok J. Shah, Michel Haı̈ssaguerre
Abstract
Open-access reader
Early repolarization (ER), consisting of a J-point elevation, notching or slurring of the terminal portion of the R wave (J wave), and tall/symmetric T wave, is a common finding on the 12-lead electrocardiogram. For decades, it has been considered as benign, barring sporadic case reports and basic electrophysiology research that suggested a critical role of the J wave in the pathogenesis of idiopathic ventricular fibrillation (VF). In 2007-2008, a high prevalence of ER in patients with idiopathic VF was reported and subsequent studies reinforced the results. This review summarizes the current state of knowledge concerning ER syndrome associated with sudden cardiac death.
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Early repolarization (ER), consisting of a J-point elevation, notching or slurring of the terminal portion of the R wave (J wave), and tall/symmetric T wave, is a common finding on the 12-lead electrocardiogram. For decades, it has been considered as benign, barring sporadic case reports and basic electrophysiology research that suggested a critical role of the J wave in the pathogenesis of idiopathic ventricular fibrillation (VF). In 2007-2008, a high prevalence of ER in patients with idiopathic VF was reported and subsequent studies reinforced the results. This review summarizes the current state of knowledge concerning ER syndrome associated with sudden cardiac death.
Key concepts: Cardiology, Sudden cardiac death, Benign early repolarization, Internal medicine, Medicine, Brugada syndrome, Repolarization, Myocardial infarction