ScholarLens Back to search
1968•UirusuOpen access

VIRAL SUSCEPTIBILITY OF AN AFRICAN GREEN MONKEY KIDNEY CELL LINE-Vero

Heihachi Itoh, Yoshio Morimoto, Yutaka Doi, Tsuneo Sanpe, Hiroshi Tsunoda

Open full text 8 citations

Abstract

An African green monkey kidney cell line, Vero was tested on its viral susceptibility to 81 laboratory strains covering Paramyxo. Influenza, Entero, Reo, Arbo, Adeno, Herpes, Papova and Poxvirus groups. A wide range of viral susceptibilities was demonstrated excepting the followings·Influenza A2 and B, and among Paramyxoviruses, HA-2, Parainfluenza type 4 and one of the two strains tested of HA-1 was nonpassable or of incomplete reproduction cycle. Coxsackie A-9 virus showed a low titer in this system. Some types of ECHO virus and one of Japanese encephalitis virus (Mukai-m) gave suggestive results for low susceptibility of this cell line. To all other virus strains tested Vero showed good sensitivity as can be used for infectivity titration and virus neutralization tests.On the chromosome analysis Vero showed several characteristics of pseudodiploid nature and cercopithecus origin.

Open-access reader

About this research paper

What this paper is about

An African green monkey kidney cell line, Vero was tested on its viral susceptibility to 81 laboratory strains covering Paramyxo. Influenza, Entero, Reo, Arbo, Adeno, Herpes, Papova and Poxvirus groups. A wide range of viral susceptibilities was demonstrated excepting the followings·Influenza A2 and B, and among Paramyxoviruses, HA-2, Parainfluenza type 4 and one of the two strains tested of HA-1 was nonpassable or of incomplete reproduction cycle. Coxsackie A-9 virus showed a low titer in this system. Some types of ECHO virus and one of Japanese encephalitis virus (Mukai-m) gave suggestive results for low susceptibility of this cell line. To all other virus strains tested Vero showed good sensitivity as can be used for infectivity titration and virus neutralization tests.On the chromosome analysis Vero showed several characteristics of pseudodiploid nature and cercopithecus origin.

Why it matters

OpenAlex reports 8 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

An African green monkey kidney cell line, Vero was tested on its viral susceptibility to 81 laboratory strains covering Paramyxo. Influenza, Entero, Reo, Arbo, Adeno, Herpes, Papova and Poxvirus groups. A wide range of viral susceptibilities was demonstrated excepting the followings·Influenza A2 and B, and among Paramyxoviruses, HA-2, Parainfluenza type 4 and one of the two strains tested of HA-1 was nonpassable or of incomplete reproduction cycle. Coxsackie A-9 virus showed a low titer in this system. Some types of ECHO virus and one of Japanese encephalitis virus (Mukai-m) gave suggestive results for low susceptibility of this cell line. To all other virus strains tested Vero showed good sensitivity as can be used for infectivity titration and virus neutralization tests.On the chromosome analysis Vero showed several characteristics of pseudodiploid nature and cercopithecus origin.

Key concepts: Vero cell, Virology, African Green Monkey, Virus, Infectivity, Biology, Titer, Virus quantification

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
VIRAL SUSCEPTIBILITY OF AN AFRICAN GREEN MONKEY KIDNEY CELL LINE-Vero — Research Paper | ScholarLens