2016RSC AdvancesRequires access

New microsecond intramolecular reactions of human telomeric DNA in solution

Cristina Pérez-Arnáiz, Natalia Busto, José M. Leal, Begoña Garcı́a

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Abstract

G-quadruplex equilibrium (type-1)-G-triplexes observed in the microsecond timescale in human telomeric DNA at pH 7.5, 0.15 M KCl. Other long-lived intermediates should not be ruled out. Similar behavior is observed in the presence of 0.15 M NaCl.

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G-quadruplex equilibrium (type-1)-G-triplexes observed in the microsecond timescale in human telomeric DNA at pH 7.5, 0.15 M KCl. Other long-lived intermediates should not be ruled out. Similar behavior is observed in the presence of 0.15 M NaCl.

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Available abstract

G-quadruplex equilibrium (type-1)-G-triplexes observed in the microsecond timescale in human telomeric DNA at pH 7.5, 0.15 M KCl. Other long-lived intermediates should not be ruled out. Similar behavior is observed in the presence of 0.15 M NaCl.

Key concepts: Microsecond, Intramolecular force, DNA, Chemistry, G-quadruplex, Stereochemistry, Crystallography, Biochemistry

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