2010The Pediatric Infectious Disease JournalRequires access

EFFECTIVENESS OF HAEMOPHILUS INFLUENZAE TYPE B CONJUGATE VACCINE FOR PREVENTION OF MENINGITIS IN SENEGAL

Jessica A. Fleming, Yakou Dieye, Ousseynou Ba, Boniface Mutombo wa Mutombo, Ndiouga Diallo, Pape Coumba Faye, Mamadou Sarifou BA, Moussa Fafa Cissé, Aïssatou Gaye Diallo, Mady Bâ, Mary Slack, Noel S. Weiss

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Abstract

A total of 24 cases of hospitalized, laboratory-confirmed Haemophilus influenzae type b (Hib) meningitis were identified through a regional pediatric bacterial meningitis surveillance system. Each case was matched by age and residence to 4 neighborhood controls. The adjusted vaccine effectiveness for ≥ 2 doses was 95.8% (95% confidence interval, 67.9%-99.4%). Hib vaccine appears to be highly effective in preventing Hib meningitis in Senegal.

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What this paper is about

A total of 24 cases of hospitalized, laboratory-confirmed Haemophilus influenzae type b (Hib) meningitis were identified through a regional pediatric bacterial meningitis surveillance system. Each case was matched by age and residence to 4 neighborhood controls. The adjusted vaccine effectiveness for ≥ 2 doses was 95.8% (95% confidence interval, 67.9%-99.4%). Hib vaccine appears to be highly effective in preventing Hib meningitis in Senegal.

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OpenAlex reports 8 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A total of 24 cases of hospitalized, laboratory-confirmed Haemophilus influenzae type b (Hib) meningitis were identified through a regional pediatric bacterial meningitis surveillance system. Each case was matched by age and residence to 4 neighborhood controls. The adjusted vaccine effectiveness for ≥ 2 doses was 95.8% (95% confidence interval, 67.9%-99.4%). Hib vaccine appears to be highly effective in preventing Hib meningitis in Senegal.

Key concepts: Meningitis, Medicine, Conjugate vaccine, Conjugate, Virology, Haemophilus influenzae, Hib vaccine, Bacterial meningitis

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