1697 THE DIRECTION AND SEVERITY OF PENILE CURVATURE DOES NOT HAVE AN IMPACT ON CONCOMITANT ERECTILE DYSFUNCTION IN PATIENTS WITH PEYRONIE'S DISEASE

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Peyronie's Disease/Surgical Therapy I1 Apr 20121697 THE DIRECTION AND SEVERITY OF PENILE CURVATURE DOES NOT HAVE AN IMPACT ON CONCOMITANT ERECTILE DYSFUNCTION IN PATIENTS WITH PEYRONIE'S DISEASE Ege Can Serefoglu, Suresh Sikka, and Wayne J.G. Hellstrom Ege Can SerefogluEge Can Serefoglu New Orleans, LA More articles by this author , Suresh SikkaSuresh Sikka New Orleans, LA More articles by this author , and Wayne J.G. HellstromWayne J.G. Hellstrom New Orleans, LA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.1592AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To determine if the degree and direction of penile curvature has any effect on presence and type of erectile dysfunction (ED) in patients with Peyronie's disease (PD). METHODS The database of our institution has been retrospectively evaluated. Doppler blood flow analyses were performed using a 10 mHz ultrasound probe after intracorporal injection of 7 to 20 micrograms (ug) of prostaglandin E1 (PGE1) by a single operator. The peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI) for each cavernosal artery were evaluated. The degree of the curvature (DoC) at peak erection was measured and the direction was recorded. The continuous variables were compared between pre-defined groups by using Kruskal Wallis test. Furthermore, the effect of ED type on DoC after controlling for the effect of patient's age was evaluated by using ANCOVA. Chi square test was used to evaluate the association between existence or direction of curvature and ED. RESULTS A total of 220 patients with PD underwent penile Doppler ultrasound assessment between 2008-2010. The mean age of the patients was 55.0±9 and 69.5% had vasculogenic ED (10% arteriogenic, 43.2% venogenic and 16.4% mixed). The mean±SE DoC was 41.7±5.2, 41.3±2.5, 37±4.1 and 37.3±3 degrees in arteriogenic, venogenic, mixed and no ED groups respectively. There was no difference between these groups in terms of DoC (all p > 0.85). Similarly direction of curvature was not affected by existence or type of ED (p=0.284). CONCLUSIONS The direction and severity of penile curvature does not have an impact on concomitant ED in patients with PD. The direction of curvature (DoC) at peak erection and its association with type of ED DoC DoC DoC DoC Total Ventral Dorsal Lateral Biplane no ED 17(40.5%) 17(23.6%) 13(24.1%) 13(35.1%) 60(29.3%) ED 25(59.5%) 55(76.4%) 41(75.9%) 24(64.9%) 145(70.7%) Arteriogenic 4(9.5%) 7(9.7%) 6(11.1%) 4(10.8%) 21(10.2%) Venogenic 13(31%) 37(51.4%) 29(53.7%) 12(32.4%) 91(44.4%) Mixed 8(19.0%) 11(15.3%) 6(11.1%) 8(21.6%) 33(16.1%) Total 42(100%) 72(100%) 54(100%) 37(100%) 205(100%) p=0.338 The degree of curvature (DoC) at peak erection and its association with type of ED Degree of Curvature Degree of Curvature ⩽45° >45° Total no ED 41(29.3%) 25(31.6%) 66(30.1%) ED 99(70.7%) 54(68.4%) 153(69.9%) Arteriogenic 12(8.6%) 10(12.7%) 22(10.0%) Venogenic 59(42.1%) 36(45.6%) 95(43.4%) Mixed 28(20.0%) 8(10.1%) 36(16.4%) Total 140(100%) 79(100%) 219(100%) p=0.255 The direction and severity of penile curvature does not have an impact on concomitant Erectile Dysfunction in patients with Peyronie's Disease. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e684-e685 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.Metrics Author Information Ege Can Serefoglu New Orleans, LA More articles by this author Suresh Sikka New Orleans, LA More articles by this author Wayne J.G. Hellstrom New Orleans, LA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...