Inhibition of Phenylbutazone Elimination by Its Metabolite Oxyphenbutazone
E. Jähnchen, Gerhard Levy
Abstract
E. Jähnchen, Gerhard Levy
Abstract
Oxyphenbutazone, a metabolite of phenylbutazone, inhibits the elimination of phenylbutazone in rats. The magnitude of this inhibitory effect is most pronounced in animals which eliminate phenylbutazone relatively rapidly in control experiments.
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Oxyphenbutazone, a metabolite of phenylbutazone, inhibits the elimination of phenylbutazone in rats. The magnitude of this inhibitory effect is most pronounced in animals which eliminate phenylbutazone relatively rapidly in control experiments.
Key concepts: Phenylbutazone, Oxyphenbutazone, Metabolite, Chemistry, Pharmacology, Biochemistry, Medicine