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Effect of Secretin and Cholecystokinin on the Response of the Gastric Fistula Rat to Pentagastrin

D. B. Tumpson, L. R. Johnson

Open publisher page 44 citations

Abstract

In rats with chronic gastric fistulas, secretin completely inhibited the gastric acid response to both maximal and supramaximal doses of pentagastrin. In the rat as in the dog, therefore, secretin is a potent inhibitor of gastrin-stimulated secretion.

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What this paper is about

In rats with chronic gastric fistulas, secretin completely inhibited the gastric acid response to both maximal and supramaximal doses of pentagastrin. In the rat as in the dog, therefore, secretin is a potent inhibitor of gastrin-stimulated secretion.

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OpenAlex reports 44 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

In rats with chronic gastric fistulas, secretin completely inhibited the gastric acid response to both maximal and supramaximal doses of pentagastrin. In the rat as in the dog, therefore, secretin is a potent inhibitor of gastrin-stimulated secretion.

Key concepts: Secretin, Pentagastrin, Internal medicine, Gastrin, Cholecystokinin, Endocrinology, Gastric acid, Gastric secretion

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Effect of Secretin and Cholecystokinin on the Response of the Gastric Fistula Rat to Pentagastrin — Research Paper | ScholarLens