Effect of Secretin and Cholecystokinin on the Response of the Gastric Fistula Rat to Pentagastrin
D. B. Tumpson, L. R. Johnson
Abstract
D. B. Tumpson, L. R. Johnson
Abstract
In rats with chronic gastric fistulas, secretin completely inhibited the gastric acid response to both maximal and supramaximal doses of pentagastrin. In the rat as in the dog, therefore, secretin is a potent inhibitor of gastrin-stimulated secretion.
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In rats with chronic gastric fistulas, secretin completely inhibited the gastric acid response to both maximal and supramaximal doses of pentagastrin. In the rat as in the dog, therefore, secretin is a potent inhibitor of gastrin-stimulated secretion.
Key concepts: Secretin, Pentagastrin, Internal medicine, Gastrin, Cholecystokinin, Endocrinology, Gastric acid, Gastric secretion