MP51-15 PRE- AND POST-OPERATIVE PREDICTORS OF INFECTION RELATED COMPLICATIONS IN PATIENTS UNDERGOING PERCUTANEOUS NEPHROLITHOTOMY

performed using 3 parameters (age, gender and race) to compare outcomes and complications between 26 patients who initially presented with sepsis prior to PNL versus a matched 52 patients (1:2 matching ratio) who did not have sepsis before PNL.RESULTS: The study included 78 patients, 56 females (72%) and 22 males (28%) with a median age of 51 (range, 18-80).There was no significant difference in demographics, stone size, stone free rate and overall complication rates between both groups (p > 0.05).The median time between treatment of sepsis and definitive treatment was 37 days (range, 3-92).Patients with prior sepsis had a significantly higher incidence of postoperative fever, greater length of hospital stay (LOS), prolonged use of antibiotics and recurrent urinary tract infection (UTI) during follow up (p < 0.05).There were no high grade in the sepsis group (5 patients developed postoperative fever and 1 patient had mild hematuria).Among those without prior sepsis, 7 (13.5%)developed high grade complications including 1 case (1.9%) of postoperative sepsis.CONCLUSIONS: Patients who will undergo PNL after treatment of urolithiasis-related sepsis may expect success and overall complication rates similar to patients without prior sepsis.However, postoperative fever and recurrent UTI may be more likely.These patients should be counseled about longer hospital stay, prolonged coverage with antibiotics after surgery and the possibility of recurrent UTI.