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Expression of candidate ivermectin resistance genes in the scabies mite, Sarcoptes scabiei

Kate Mounsey, Debra Holt, James McCarthy, Bart J. Currie, Shelley F. Walton

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Abstract

Oral ivermectin (IVM) is increasingly used to treat ordinary scabies, and is the drug of choice in northern Australia for hyper-infested (crusted) scabies. Reports of ivermectin resistance in crusted scabies raise concerns regarding the sustainability of this relatively new drug for scabies. In light of increasing ivermectin use, and its likely incorporation into community mass treatment programs, it is critical to define mechanisms of ivermectin resistance in scabies mites.

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What this paper is about

Oral ivermectin (IVM) is increasingly used to treat ordinary scabies, and is the drug of choice in northern Australia for hyper-infested (crusted) scabies. Reports of ivermectin resistance in crusted scabies raise concerns regarding the sustainability of this relatively new drug for scabies. In light of increasing ivermectin use, and its likely incorporation into community mass treatment programs, it is critical to define mechanisms of ivermectin resistance in scabies mites.

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Available abstract

Oral ivermectin (IVM) is increasingly used to treat ordinary scabies, and is the drug of choice in northern Australia for hyper-infested (crusted) scabies. Reports of ivermectin resistance in crusted scabies raise concerns regarding the sustainability of this relatively new drug for scabies. In light of increasing ivermectin use, and its likely incorporation into community mass treatment programs, it is critical to define mechanisms of ivermectin resistance in scabies mites.

Key concepts: Ivermectin, Scabies, Sarcoptes scabiei, Mite, Biology, Drug resistance, Veterinary medicine, Dermatology

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Expression of candidate ivermectin resistance genes in the scabies mite, Sarcoptes scabiei — Research Paper | ScholarLens