2011•The Pediatric Infectious Disease JournalRequires access
Mixtures of Oseltamivir-sensitive and -resistant Pandemic Influenza A/H1N1/2009 Viruses in Immunocompromised Hospitalized Children
Mas Suhaila, Julian Wei-Tze Tang, Hong Kai Lee, Cui Lin, Paul Anantharajah Tambyah, Hui‐Kim Yap, Seng Hock Quak, Evelyn Siew-Chuan Koay
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Abstract
We report on 3 immunocompromised children infected with pandemic influenza A/H1N1/2009 in whom mixtures of oseltamivir-susceptible and oseltamivir-resistant viral populations developed, despite them receiving relatively short-term courses of oseltamivir. In addition, it was found that bacterial coinfections were common, indicating that empiric, antibiotics should be considered in such patients when infected with influenza virus.