Malignant hyperthermia: advances in diagnostics and management
P Adnet, Gerald A. Gronert
Abstract
P Adnet, Gerald A. Gronert
Abstract
Real-time monitoring of end-tidal carbon dioxide during anaesthesia aids in the early detection of malignant hyperthermia and the occurrence of a rapid increase in end-tidal carbon dioxide, associated with unexplained persistent tachycardia, well before the core temperature begins to rise. Should malignant hyperthermia occur, however, dantrolene permits the dependable reversal of skeletal muscle hypermetabolism.
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Real-time monitoring of end-tidal carbon dioxide during anaesthesia aids in the early detection of malignant hyperthermia and the occurrence of a rapid increase in end-tidal carbon dioxide, associated with unexplained persistent tachycardia, well before the core temperature begins to rise. Should malignant hyperthermia occur, however, dantrolene permits the dependable reversal of skeletal muscle hypermetabolism.
Key concepts: Malignant hyperthermia, Medicine, Dantrolene, Hypermetabolism, Hyperthermia, Tachycardia, Anesthesia, Carbon dioxide