Expression of heat shock proteins 27, 60 and 70 in oral carcinogenesis: An immunohistochemical study
Merva Soluk Tekkeşin
Abstract
Merva Soluk Tekkeşin
Abstract
Heat shock proteins (HSPs) are a class of functionally related proteins, the expression of which is increased when cells are exposed to elevated temperatures or other stresses, including infection, irradiation, heavy metals, ethanol, and oxidants. The aim of this study was to investigate the significance of HSP60, HSP70 and HSP27 as prognostic factors in different stages of oral carcinogenesis by immunohistochemical analysis.
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Heat shock proteins (HSPs) are a class of functionally related proteins, the expression of which is increased when cells are exposed to elevated temperatures or other stresses, including infection, irradiation, heavy metals, ethanol, and oxidants. The aim of this study was to investigate the significance of HSP60, HSP70 and HSP27 as prognostic factors in different stages of oral carcinogenesis by immunohistochemical analysis.
Key concepts: Immunohistochemistry, Heat shock protein, Medicine, Carcinogenesis, Shock (circulatory), Hsp70, Pathology, Cancer research