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2013•American Journal of NeuroradiologyOpen access

On the Role of Screening for Intracranial Aneurysms in Autosomal Dominant Polycystic Kidney Disease

Joshua P. Klein

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Abstract

Intracranial aneurysm (ICAN) formation is a well-known complication in patients with autosomal dominant polycystic kidney disease (ADPKD). In these patients, aneurysms are thought to form as a consequence of abnormal polycystin protein expression in vascular myocytes, which impairs the structural

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Intracranial aneurysm (ICAN) formation is a well-known complication in patients with autosomal dominant polycystic kidney disease (ADPKD). In these patients, aneurysms are thought to form as a consequence of abnormal polycystin protein expression in vascular myocytes, which impairs the structural

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Available abstract

Intracranial aneurysm (ICAN) formation is a well-known complication in patients with autosomal dominant polycystic kidney disease (ADPKD). In these patients, aneurysms are thought to form as a consequence of abnormal polycystin protein expression in vascular myocytes, which impairs the structural

Key concepts: Autosomal dominant polycystic kidney disease, Medicine, Polycystic kidney, Complication, Polycystic kidney disease, Aneurysm, Disease, Kidney

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