Hemagglutination and Hemagglutination-Inhibition with Adenovirus Type 12.
Nathalie J. Schmidt, Charly King, E. H. Lennette
Abstract
Nathalie J. Schmidt, Charly King, E. H. Lennette
Abstract
Hemagglutmation has been demonstrated with the prototype Huie strain and two nonprototype strains of adenovirus type 12. This viral type resembles those classified in Group 3 in that hemagglutination occurred with rat cells in the presence of hetero-typic immune serum. Hemagglutination was specifically inhibited by immune serum to adenovirus type 12, but not immune serum to other adenoviruses. The identity of the hemagglutinating virus as adenovirus type 12 was confirmed by both hemagglutination–inhibition and neutralization tests with reference immune sera prepared in other laboratories.
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Hemagglutmation has been demonstrated with the prototype Huie strain and two nonprototype strains of adenovirus type 12. This viral type resembles those classified in Group 3 in that hemagglutination occurred with rat cells in the presence of hetero-typic immune serum. Hemagglutination was specifically inhibited by immune serum to adenovirus type 12, but not immune serum to other adenoviruses. The identity of the hemagglutinating virus as adenovirus type 12 was confirmed by both hemagglutination–inhibition and neutralization tests with reference immune sera prepared in other laboratories.
Key concepts: Hemagglutination, Hemagglutination assay, Virology, Immune system, Biology, Neutralization, Virus, Microbiology