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Nutritional Studies with the Guinea Pig. B-Vitamins other than Pantothenic Acid.

Mary Elizabeth Reid

Open publisher page 20 citations

Abstract

A determination has been made of the essentiality or non-essentiality of vitamins of the B group as components of a semi-synthetic diet developed especially for guinea pigs. Clear-cut deficiencies of choline, pyridoxine, and riboflavin were produced for the first time. In addition, a dietary need of thiamine, niacin, and folic acid has been confirmed. It appears that in the presence of an adequate supply of folic acid, PABA is not essential in the diet. Under our conditions no requirement has yet been demonstrated for inositol, biotin, or vit. B12.

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A determination has been made of the essentiality or non-essentiality of vitamins of the B group as components of a semi-synthetic diet developed especially for guinea pigs. Clear-cut deficiencies of choline, pyridoxine, and riboflavin were produced for the first time. In addition, a dietary need of thiamine, niacin, and folic acid has been confirmed. It appears that in the presence of an adequate supply of folic acid, PABA is not essential in the diet. Under our conditions no requirement has yet been demonstrated for inositol, biotin, or vit. B12.

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Available abstract

A determination has been made of the essentiality or non-essentiality of vitamins of the B group as components of a semi-synthetic diet developed especially for guinea pigs. Clear-cut deficiencies of choline, pyridoxine, and riboflavin were produced for the first time. In addition, a dietary need of thiamine, niacin, and folic acid has been confirmed. It appears that in the presence of an adequate supply of folic acid, PABA is not essential in the diet. Under our conditions no requirement has yet been demonstrated for inositol, biotin, or vit. B12.

Key concepts: Pantothenic acid, Riboflavin, Niacin, Pyridoxine, Thiamine, B vitamins, Biotin, Folic acid

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