Imatinib Dose Interruption in GIST: High Progression Risk for 3-YearResponders
Caroline Helwick, Axel Le Cesne
Abstract
Caroline Helwick, Axel Le Cesne
Abstract
This article discusses multiple clinical trials using imatinib for the treatment of gastrointestinal stromal tumor (GIST). Specific topics include the risk associated with the interruption of imatinib therapy among advanced GIST patients, the link between higher doese of imatinib for GIST and longer progression-free survival, as well as the use of imatinib for recurrence-free survival in completely resected GIST.
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This article discusses multiple clinical trials using imatinib for the treatment of gastrointestinal stromal tumor (GIST). Specific topics include the risk associated with the interruption of imatinib therapy among advanced GIST patients, the link between higher doese of imatinib for GIST and longer progression-free survival, as well as the use of imatinib for recurrence-free survival in completely resected GIST.
Key concepts: GiST, Imatinib, Medicine, Stromal tumor, Oncology, Internal medicine, Imatinib mesylate, Stromal cell