2006Practica Oto-Rhino-LaryngologicaOpen access

Two Cases of Solitary Fibrous Tumor

Akiko Tani, Yukio Nomoto, Mutsumi Watanabe, Makoto Kano, Koichi Omori

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Abstract

We report 2 cases of solitary fibrous tumor (SFT). SFT usually involves the pleura and rarely involves the head and neck lesion.The first patient was a 32-year-old female who complained of right oral base swelling. Computed tomography showed a high density mass in the right oral floor. The encapsulated tumor was removed and the tumor cells were immunohistochemically determined to be positive for vimentin and CD34; demonstrating characteristics of SFT.The second patient was a 49-old-female who complained of left submandibular swelling. Computed tomography showed an enhanced mass. The tumor was removed with a submandibular gland. The tumor cells were immunohistochemically determined to be positive for CD34.In both cases, although preoperative diagnosis was difficult, immunohistochemical examinations obtained the correct diagnosis.

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We report 2 cases of solitary fibrous tumor (SFT). SFT usually involves the pleura and rarely involves the head and neck lesion.The first patient was a 32-year-old female who complained of right oral base swelling. Computed tomography showed a high density mass in the right oral floor. The encapsulated tumor was removed and the tumor cells were immunohistochemically determined to be positive for vimentin and CD34; demonstrating characteristics of SFT.The second patient was a 49-old-female who complained of left submandibular swelling. Computed tomography showed an enhanced mass. The tumor was removed with a submandibular gland. The tumor cells were immunohistochemically determined to be positive for CD34.In both cases, although preoperative diagnosis was difficult, immunohistochemical examinations obtained the correct diagnosis.

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Available abstract

We report 2 cases of solitary fibrous tumor (SFT). SFT usually involves the pleura and rarely involves the head and neck lesion.The first patient was a 32-year-old female who complained of right oral base swelling. Computed tomography showed a high density mass in the right oral floor. The encapsulated tumor was removed and the tumor cells were immunohistochemically determined to be positive for vimentin and CD34; demonstrating characteristics of SFT.The second patient was a 49-old-female who complained of left submandibular swelling. Computed tomography showed an enhanced mass. The tumor was removed with a submandibular gland. The tumor cells were immunohistochemically determined to be positive for CD34.In both cases, although preoperative diagnosis was difficult, immunohistochemical examinations obtained the correct diagnosis.

Key concepts: Solitary fibrous tumor, CD34, Vimentin, Medicine, Immunohistochemistry, Lesion, Head and neck, Submandibular gland

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