2011•Iranian journal of pathologyRequires access

Giant Cell Ependymoma of The Filum Terminale: A Case Report

Nona Zabolinejad, Taraz Jamshidi Shirin, Rafati Alireza, Kamran Ghafarzadegan

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Abstract

Ependymomas accounts for about 2%–6% of CNS and 60%–70% of spinal cord tumors. Several histological patterns of these neoplasms are well known, but little attention has been devoted to a variant composed of giant cells. In spite of apparently “worrisome” histology, giant cell ependymoma seems to be a neoplasm with a relatively good prognosis. This report presents a case of giant cell ependymoma of the filum terminale in a 24-year-old woman and highlights the morphological diagnostic criteria for this rare tumor.

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What this paper is about

Ependymomas accounts for about 2%–6% of CNS and 60%–70% of spinal cord tumors. Several histological patterns of these neoplasms are well known, but little attention has been devoted to a variant composed of giant cells. In spite of apparently “worrisome” histology, giant cell ependymoma seems to be a neoplasm with a relatively good prognosis. This report presents a case of giant cell ependymoma of the filum terminale in a 24-year-old woman and highlights the morphological diagnostic criteria for this rare tumor.

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Available abstract

Ependymomas accounts for about 2%–6% of CNS and 60%–70% of spinal cord tumors. Several histological patterns of these neoplasms are well known, but little attention has been devoted to a variant composed of giant cells. In spite of apparently “worrisome” histology, giant cell ependymoma seems to be a neoplasm with a relatively good prognosis. This report presents a case of giant cell ependymoma of the filum terminale in a 24-year-old woman and highlights the morphological diagnostic criteria for this rare tumor.

Key concepts: Filum terminale, Ependymoma, Giant cell, Spinal cord, Pathology, Histology, Medicine, Psychiatry

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