Growth and Mortality Effects Produced in the Early Chick Embryo By Antiserum

Using the described experimental conditions whole anti-chick embryo hamster serum placed in proximity to the pre-incubated chick embryo stops the development of these embryos at a time which corresponds to the time the embryo antigen was obtained. Even though the experimental factors are complex the experimental series differed sharply from the controls. The anti-embryo serum also produced anomalies and a high mortality in the treated series. These experiments show clearly that chick embryos contain distinctive antigenic materials which are related to the embryo's age. The instep order of the results in the recipient embryos points strongly to the development of qualitatively different protein complexes in the embryo concurrent with the embryo's growth