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1972•The Journal of Infectious DiseasesRequires access

The Slow Bactericidal Effect of Tetracycline and Minocycline on Wall-Defective Staphylococcus

Judith Carleton, John Phair

Open publisher page 7 citations

Abstract

Tetracycline and minocycline have a slow bactericidal effect upon both parent Staphylococcus aureus and variants with defective cell walls. Flasks containing between 5 × 105 and 5 × 106 wall-defective staphylococci were sterilized within seven to nine days if the concentration of either antibiotic was maintained at 10–500 times the minimal inhibitory concentration.

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What this paper is about

Tetracycline and minocycline have a slow bactericidal effect upon both parent Staphylococcus aureus and variants with defective cell walls. Flasks containing between 5 × 105 and 5 × 106 wall-defective staphylococci were sterilized within seven to nine days if the concentration of either antibiotic was maintained at 10–500 times the minimal inhibitory concentration.

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OpenAlex reports 7 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Tetracycline and minocycline have a slow bactericidal effect upon both parent Staphylococcus aureus and variants with defective cell walls. Flasks containing between 5 × 105 and 5 × 106 wall-defective staphylococci were sterilized within seven to nine days if the concentration of either antibiotic was maintained at 10–500 times the minimal inhibitory concentration.

Key concepts: Minocycline, Tetracycline, Staphylococcus aureus, Microbiology, Minimum inhibitory concentration, Staphylococcus, Antibiotics, Laboratory flask

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