2000•日本臨床細胞学会雑誌Open access

A case of BCG-related lymphadenitis.

Yasushi Horie, Masako Kato, Mitsuko Nagami, Chieko SUGIHARA, Shoji Yashima

Abstract

A case of BCG-related lymphadenitis is presented. After BCG vaccination, an enlarging mass was noted in the left axillary region of a 1-year-old boy. Imprint smear cytology of the extirpated lesion revealed aggregates of epithelioid and tingible-type histiocytic cells without a necrotic background. Histologically, the lesion showed granulomatous nodules composed of epithelioid histiocytic cells and Langhans' giant cells without associated caseous necrosis. Immunohistochemically, the epithelioid histiocytic cells were positive for and-BCG antibody, lysozyme and CD 68. It is necessary to distinguish this BCG-related lymphadenitis from tuberculous lymphadenitis.

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Key concepts: Langhans giant cell, Epithelioid cell, Histiocyte, Caseous necrosis, Medicine, Giant cell, Pathology, Tuberculous lymphadenitis