1966•Experimental Biology and MedicineRequires access
Effect of Hypertrophy on Myocardial Distensibility
J. F. Williams, Edmund H. Sonnenblick, Eugene Braunwald
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Abstract
Length-resting tension curves were recorded from strips of left ventricle obtained from 10 rats with myocardial hypertrophy produced by subdiaphragmatic suprarenal aortic constriction, and 8 rats subjected to aortic constriction in which hypertrophy did not develop. No differences were noted between the distensibility of the normal and hypertrophied myocardium after corrections were made for differences in muscle mass and cross-sectional area.