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Chronic granulomatous disease - primary phagocytic immunodeficiency

Boena Polañska

Open publisher page 3 citations

Abstract

Chronic granulomatous disease (CGD) is a rare hereditary primary immunodeficiency, in which defective production of microbicidal oxidants by phagocytes (neutrophils, eosinophils, monocytes, and macrophages) leads to severe recurrent infections. This article reviews pathogenesis, diagnostic criteria, clinical signs, and treatment of CGD.

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What this paper is about

Chronic granulomatous disease (CGD) is a rare hereditary primary immunodeficiency, in which defective production of microbicidal oxidants by phagocytes (neutrophils, eosinophils, monocytes, and macrophages) leads to severe recurrent infections. This article reviews pathogenesis, diagnostic criteria, clinical signs, and treatment of CGD.

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OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Chronic granulomatous disease (CGD) is a rare hereditary primary immunodeficiency, in which defective production of microbicidal oxidants by phagocytes (neutrophils, eosinophils, monocytes, and macrophages) leads to severe recurrent infections. This article reviews pathogenesis, diagnostic criteria, clinical signs, and treatment of CGD.

Key concepts: Chronic granulomatous disease, Primary immunodeficiency, Immunology, Pathogenesis, Immunodeficiency, Medicine, Granulomatous disease, Disease

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