Deposition of C14-Labelled Cholesterol in the Atheromatous Aorta.

The results suggest that circulating cholesterol exchanges with available cholesterol pools of intima of human aorta. This exchange is slow. Cholesterol in the atheromatous plaques appears to exchange or accept circulatory cholesterol with the greatest difficulty. The highest exchange or depositions were observed for area of the arch of human aorta; abdominal part of aorta showed a smaller exchange. The media showed about the same cholesterol rate of exchange through length of aorta. A disk technic suitable for various types of quantitative assays of intima, media, etc. of the aorta was described.