1995•Biological and Pharmaceutical BulletinOpen access

Absorption of (-)-Epigallocatechin Gallate into Rat Portal Vein.

Kazuo Okushio, Natsuki MATSUMOTO, Masayuki Suzuki, Fumio Nanjo, Yukihiko HARA

Abstract

Following oral administration of (-)-epigallocatechin gallate to rats, the presence of (-)-epigallocatechin gallate was examined in the portal blood. A compound present in the blood was identified as (-)-epigallocatechin gallate by HPLC and mass spectrometry analysis. The results clearly demonstrate that (-)-epigallocatechin gallate is absorbed, at least in part, into rat portal blood.

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Key concepts: Gallate, Epigallocatechin gallate, Oral administration, Absorption (acoustics), Chemistry, High-performance liquid chromatography, Portal vein, Pharmacology