Sustained Molecular Remission after Arsenic Trioxide and Gemutuzumab Ozogamicin in a Pediatric Patient with Relapsed Acute Promyelocytic Leukemia
Akiko Inoue, Chihiro Kawakami, Kimitaka Takitani, Hiroshi Tamai
Abstract
Akiko Inoue, Chihiro Kawakami, Kimitaka Takitani, Hiroshi Tamai
Abstract
Acute promyelocytic leukemia (APL) is characterized by a specific chromosomal translocation, t(15;17)(q22;q21), which leads to a promyelocytic leukemia (PML) - retinoic acid receptor α (RARα) fusio...
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Acute promyelocytic leukemia (APL) is characterized by a specific chromosomal translocation, t(15;17)(q22;q21), which leads to a promyelocytic leukemia (PML) - retinoic acid receptor α (RARα) fusio...
Key concepts: Arsenic trioxide, Acute promyelocytic leukemia, Medicine, Promyelocytic leukemia protein, Leukemia, Chromosomal translocation, Cancer research, Retinoic acid