2015Clinical Cancer Investigation JournalOpen access

Primary signet-ring cell carcinoma of gallbladder resembling linitis plastica: A clinical impostor of chronic cholecystitis

Krishnendu Mondal, Rupali Mandal

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Abstract

Primary signet-ring cell carcinoma (SRCC) is an extremely rare and aggressive type of malignant gallbladder (GB) neoplasm, which is comprised predominantly (>50%) of signet-ring cells. Owing to its diffusely invading nature, SRCC often confers a "linitis plastica" like appearance to GB. Such a gross morphology in the background of nonspecific clinical presentation creates confusion with several other benign and more common pathological entities. This dilemma can effectively be settled through cl

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Primary signet-ring cell carcinoma (SRCC) is an extremely rare and aggressive type of malignant gallbladder (GB) neoplasm, which is comprised predominantly (>50%) of signet-ring cells. Owing to its diffusely invading nature, SRCC often confers a "linitis plastica" like appearance to GB. Such a gross morphology in the background of nonspecific clinical presentation creates confusion with several other benign and more common pathological entities. This dilemma can effectively be settled through cl

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Available abstract

Primary signet-ring cell carcinoma (SRCC) is an extremely rare and aggressive type of malignant gallbladder (GB) neoplasm, which is comprised predominantly (>50%) of signet-ring cells. Owing to its diffusely invading nature, SRCC often confers a "linitis plastica" like appearance to GB. Such a gross morphology in the background of nonspecific clinical presentation creates confusion with several other benign and more common pathological entities. This dilemma can effectively be settled through cl

Key concepts: Linitis plastica, Medicine, Gallbladder, Signet ring cell carcinoma, Signet ring cell, Carcinoma, Gastroenterology, Chronic cholecystitis

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