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Effect of Treatment with Growth Hormone on Somatostatin in the Median Eminence of Hypophysectomized Rats

David L. Hoffman, B. L. Baker

Open publisher page 42 citations

Abstract

Treatment of rats with growth hormone partially prevented depletion of somatostatin from the median eminence when therapy was begun immediately following hypophysectomy, and partially restored somatostatin when treatment was initiated after a prolonged posthypophysec-tomy interval. These observations suggest that growth hormone tends to increase the store of somatostatin in the median eminence.

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What this paper is about

Treatment of rats with growth hormone partially prevented depletion of somatostatin from the median eminence when therapy was begun immediately following hypophysectomy, and partially restored somatostatin when treatment was initiated after a prolonged posthypophysec-tomy interval. These observations suggest that growth hormone tends to increase the store of somatostatin in the median eminence.

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OpenAlex reports 42 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Treatment of rats with growth hormone partially prevented depletion of somatostatin from the median eminence when therapy was begun immediately following hypophysectomy, and partially restored somatostatin when treatment was initiated after a prolonged posthypophysec-tomy interval. These observations suggest that growth hormone tends to increase the store of somatostatin in the median eminence.

Key concepts: Median eminence, Somatostatin, Hypophysectomy, Internal medicine, Endocrinology, Growth hormone, Hormone, Medicine

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Effect of Treatment with Growth Hormone on Somatostatin in the Median Eminence of Hypophysectomized Rats — Research Paper | ScholarLens