Antigenic Diversity of Infectious Bursal Disease Viruses
D H Jackwood, Y. Μ. Saif
Abstract
D H Jackwood, Y. Μ. Saif
Abstract
Statistically significant antigenic differences were detected among serotype I infectious bursal disease viruses (IBDV) using the virus-neutralization test. Eight serotype I commercial vaccine strains, five serotype I field strains, and two serotype II field strains were tested. Hyperimmune guinea pig antisera against heterologous and homologous IBDV strains were used in cross-neutralization tests. Relatedness values were calculated from geometric mean antibody titers based on a minimum of three tests. Six subtypes were distinguished among the 13 serotype I strains tested.
OpenAlex reports 285 citations for this work. Citation counts describe recorded attention and do not establish research quality.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Statistically significant antigenic differences were detected among serotype I infectious bursal disease viruses (IBDV) using the virus-neutralization test. Eight serotype I commercial vaccine strains, five serotype I field strains, and two serotype II field strains were tested. Hyperimmune guinea pig antisera against heterologous and homologous IBDV strains were used in cross-neutralization tests. Relatedness values were calculated from geometric mean antibody titers based on a minimum of three tests. Six subtypes were distinguished among the 13 serotype I strains tested.
Key concepts: Infectious bursal disease, Serotype, Biology, Virology, Heterologous, Virus, Antiserum, Neutralization