1963Experimental Biology and MedicineRequires access

Colchicine Teratogenesis in Hamster Embryos.

Vergil H. Ferm

Open publisher page 36 citations

Abstract

Colchicine injected intravenously into pregnant hamsters on the 8th day of gestation at levels of 10 mg kg produces a fetal mortality of 50%. Gross congenital malformations, consisting of microphthalmia, anophthalmia, umbilical hernia, exencephaly, and skeletal anomalies are found in a significant number of survivors.

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What this paper is about

Colchicine injected intravenously into pregnant hamsters on the 8th day of gestation at levels of 10 mg kg produces a fetal mortality of 50%. Gross congenital malformations, consisting of microphthalmia, anophthalmia, umbilical hernia, exencephaly, and skeletal anomalies are found in a significant number of survivors.

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OpenAlex reports 36 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Colchicine injected intravenously into pregnant hamsters on the 8th day of gestation at levels of 10 mg kg produces a fetal mortality of 50%. Gross congenital malformations, consisting of microphthalmia, anophthalmia, umbilical hernia, exencephaly, and skeletal anomalies are found in a significant number of survivors.

Key concepts: Colchicine, Embryo, Hamster, Andrology, Biology, Cell biology, Genetics, Medicine

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