Colchicine Teratogenesis in Hamster Embryos.
Vergil H. Ferm
Abstract
Vergil H. Ferm
Abstract
Colchicine injected intravenously into pregnant hamsters on the 8th day of gestation at levels of 10 mg kg produces a fetal mortality of 50%. Gross congenital malformations, consisting of microphthalmia, anophthalmia, umbilical hernia, exencephaly, and skeletal anomalies are found in a significant number of survivors.
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Colchicine injected intravenously into pregnant hamsters on the 8th day of gestation at levels of 10 mg kg produces a fetal mortality of 50%. Gross congenital malformations, consisting of microphthalmia, anophthalmia, umbilical hernia, exencephaly, and skeletal anomalies are found in a significant number of survivors.
Key concepts: Colchicine, Embryo, Hamster, Andrology, Biology, Cell biology, Genetics, Medicine