2009Practica Oto-Rhino-LaryngologicaRequires access

Clinical Study of IgA Nephropathy after Tonsillectomy

Keiko Ohkubo, Yoshihisa Ueda, Takeharu Ono, Tadashi Nakashima

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Abstract

We reviewed the clinical effect of tonsillectomy against IgA nephropathy in 34 patients who had received tonsillectomies (group A) and compared the results with 58 patients who were treated without surgery (group B). For analysis, we used the IgA score for renal pathology, and examined the clinical remission rate, stable renal function rate and the renal survival rate. The clinical remission rate was 35% in group A and 16% in group B, but there was no significant difference between the two groups (p=0.03). The stable renal function rate was 85% in group A and 67% in group B, but there was no significant difference between the two groups (p=0.06). Our results showed that tonsillectomy is a clinically effective treatment for IgA nephropathy, however, it is necessary to perform long-term follow-up.

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What this paper is about

We reviewed the clinical effect of tonsillectomy against IgA nephropathy in 34 patients who had received tonsillectomies (group A) and compared the results with 58 patients who were treated without surgery (group B). For analysis, we used the IgA score for renal pathology, and examined the clinical remission rate, stable renal function rate and the renal survival rate. The clinical remission rate was 35% in group A and 16% in group B, but there was no significant difference between the two groups (p=0.03). The stable renal function rate was 85% in group A and 67% in group B, but there was no significant difference between the two groups (p=0.06). Our results showed that tonsillectomy is a clinically effective treatment for IgA nephropathy, however, it is necessary to perform long-term follow-up.

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Available abstract

We reviewed the clinical effect of tonsillectomy against IgA nephropathy in 34 patients who had received tonsillectomies (group A) and compared the results with 58 patients who were treated without surgery (group B). For analysis, we used the IgA score for renal pathology, and examined the clinical remission rate, stable renal function rate and the renal survival rate. The clinical remission rate was 35% in group A and 16% in group B, but there was no significant difference between the two groups (p=0.03). The stable renal function rate was 85% in group A and 67% in group B, but there was no significant difference between the two groups (p=0.06). Our results showed that tonsillectomy is a clinically effective treatment for IgA nephropathy, however, it is necessary to perform long-term follow-up.

Key concepts: Tonsillectomy, Medicine, Nephropathy, Renal function, Group B, Gastroenterology, Group A, Internal medicine

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