ScholarLens Back to search
1953•Experimental Biology and MedicineRequires access

Biochemical Changes in Thermally-Injured Cutaneous Tissue, Susceptibility to Proteolytic Enzymes, and Extractability of Collagen

A. E. Axelrod, C. J. Martin

Open publisher page 10 citations

Abstract

1. The effects of in vitro (50-100° C) and in situ (55° and 70° C) hydro-thermal injury upon susceptibility of the abdominal skin of rats to peptic and tryptic digestion were determined. The action of pepsin upon unheated skin was considerably greater than that of trypsin; whereas heating both in vitro and in situ, increased only the susceptibility toward trypsin. 2. Similai hydrothermal exposures produced changes ir rat skin and tail tendon collagens which rendered them extractable by normal saline.

About this research paper

What this paper is about

1. The effects of in vitro (50-100° C) and in situ (55° and 70° C) hydro-thermal injury upon susceptibility of the abdominal skin of rats to peptic and tryptic digestion were determined. The action of pepsin upon unheated skin was considerably greater than that of trypsin; whereas heating both in vitro and in situ, increased only the susceptibility toward trypsin. 2. Similai hydrothermal exposures produced changes ir rat skin and tail tendon collagens which rendered them extractable by normal saline.

Why it matters

OpenAlex reports 10 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

1. The effects of in vitro (50-100° C) and in situ (55° and 70° C) hydro-thermal injury upon susceptibility of the abdominal skin of rats to peptic and tryptic digestion were determined. The action of pepsin upon unheated skin was considerably greater than that of trypsin; whereas heating both in vitro and in situ, increased only the susceptibility toward trypsin. 2. Similai hydrothermal exposures produced changes ir rat skin and tail tendon collagens which rendered them extractable by normal saline.

Key concepts: Pepsin, Trypsin, In vitro, Proteolytic enzymes, Chemistry, Saline, Enzyme, Digestion (alchemy)

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Biochemical Changes in Thermally-Injured Cutaneous Tissue, Susceptibility to Proteolytic Enzymes, and Extractability of Collagen — Research Paper | ScholarLens