Factors Affecting Tissue Oxygenation in Erythrocyte Transfusions
Güçlü Aykut, Koray Yürük, Can İnce
Abstract
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Güçlü Aykut, Koray Yürük, Can İnce
Abstract
Open-access reader
Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states. But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation. Also, the patient situation may play a role in the differing responses in oxygenation and microcirculation. In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.
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Red blood cell transfusions are used to increase the oxygen-carrying capacity of blood in anemic states. But, because of the changes during storage of blood components and the specifics of preparation, erythrocytes may have controversial effects on tissue oxygenation and microcirculation. Also, the patient situation may play a role in the differing responses in oxygenation and microcirculation. In this review, the studies concerning the effects of banked blood and patient characteristics on microcirculation and tissue oxygenation are summarized.
Key concepts: Microcirculation, Oxygenation, Medicine, Blood oxygenation, Red blood cell, Intensive care medicine, Internal medicine, Functional magnetic resonance imaging