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Characterization of a New Infectious Bronchitis Virus Isolate I. Serological and Pathogenicity Studies of Clark 333

BARRETT S. COWEN, Stephen B. Hitchner, Benjamin Lucio

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Abstract

An infectious bronchitis-like virus was isolated from a flock of 7-week-old pullets which had not been vaccinated with infectious bronchitis virus (IBV). The virus, designated Clark 333, produced clinical signs in birds and lesions in chicken embryos characteristic of IBV and did not cause hemagglutination. Fluorescent antibody and cross-protection tests demonstrated this isolate's antigenic relatedness to IBV by virtue of a one-way cross with the Connecticut subtype. No cross reaction occurred with serum neutralization tests.

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What this paper is about

An infectious bronchitis-like virus was isolated from a flock of 7-week-old pullets which had not been vaccinated with infectious bronchitis virus (IBV). The virus, designated Clark 333, produced clinical signs in birds and lesions in chicken embryos characteristic of IBV and did not cause hemagglutination. Fluorescent antibody and cross-protection tests demonstrated this isolate's antigenic relatedness to IBV by virtue of a one-way cross with the Connecticut subtype. No cross reaction occurred with serum neutralization tests.

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Available abstract

An infectious bronchitis-like virus was isolated from a flock of 7-week-old pullets which had not been vaccinated with infectious bronchitis virus (IBV). The virus, designated Clark 333, produced clinical signs in birds and lesions in chicken embryos characteristic of IBV and did not cause hemagglutination. Fluorescent antibody and cross-protection tests demonstrated this isolate's antigenic relatedness to IBV by virtue of a one-way cross with the Connecticut subtype. No cross reaction occurred with serum neutralization tests.

Key concepts: Biology, Serology, Pathogenicity, Virology, Infectious bronchitis virus, Avian infectious bronchitis virus, Virus, Microbiology

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Characterization of a New Infectious Bronchitis Virus Isolate I. Serological and Pathogenicity Studies of Clark 333 — Research Paper | ScholarLens