Exploring the Value and Costs of Incretin-Based Therapies
Daniel O. Bittner, Clifford J. Bailey
Abstract
Daniel O. Bittner, Clifford J. Bailey
Abstract
The development of incretin-based therapies over the past decade since the approval of exenatide has opened new possibilities for the treatment of type 2 diabetes mellitus (T2DM). This article discusses the various metabolic activities of endogenous GLP-1 and DPP-4 antagonists, the side effects of incretin-based therapies, and the need for new diabetes treatments.
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The development of incretin-based therapies over the past decade since the approval of exenatide has opened new possibilities for the treatment of type 2 diabetes mellitus (T2DM). This article discusses the various metabolic activities of endogenous GLP-1 and DPP-4 antagonists, the side effects of incretin-based therapies, and the need for new diabetes treatments.
Key concepts: Exenatide, Incretin, Medicine, Diabetes mellitus, Type 2 Diabetes Mellitus, Intensive care medicine, Type 2 diabetes, Liraglutide