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Yeast-Growth-Promoting Effect of Diaminocarboxylic Acid Derived from Biotin.

Vincent du Vigneaud, Karl Dittmer, Kay Hofmann, Donald B. Melville

Abstract

The diaminocarboxylie acid resulting from the hydrolysis of the urea ring of biotin is capable of stimulating the growth of yeast in a biotin-free medium. The compound possesses about 10% of the activity of biotin. The yeast-growth-promoting activity of the diaminocarboxylic acid is not inhibited by avidin.

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Available abstract

Key concepts: Biotin, Yeast, Biochemistry, Avidin, Vitamin b complex, Hydrolysis, Chemistry, Urea