2010•Ghent University Academic Bibliography (Ghent University)Open access
Role of p21-activated kinases 1 and 2 in pseudorabies virus US3-mediated effects on apoptosis and nuclear egress
Céline Van den Broeke, Charles S. Hoffman, Hans Nauwynck, Wim Van Den Broeck, Jonathan Chernoff, Herman W. Favoreel
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Abstract
The pseudorabies virus (PRV) is a member of the alphaherpesvirus subfamily of the herpesviruses, and is often used as a model to study general aspects of this virus subfamily (Pomeranz et al., 2005, Microbiol Mol Biol Rev). The alphaherpesvirus subfamily contains closely related viruses of man and animal, including the human herpes simplex virus type 1 and type 2 and varicella zoster virus and different animal pathogens, including PRV in pigs, equine herpesvirus 1 in horses, bovine herpesvirus 1 in cattle, and Marek’s disease virus in poultry.
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