2014中国医学文摘:内科学分册(英文版)Requires access

Induction in vitro and stability of Mycobacterium tuberculosis resistance to ofloxacin

杨华

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Abstract

Objective To induct Mycobacterium tuberculosis(MTB)resistance with ofloxacin(Ofx)of stepwise increasing concentration in vitro,investigate stability to fluoroquinolone(FQs)antibiotic of MTB,and analyze the molecular mechanism and mutation specialty of drug resistance preliminarily.Methods MTB Standard strain

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Objective To induct Mycobacterium tuberculosis(MTB)resistance with ofloxacin(Ofx)of stepwise increasing concentration in vitro,investigate stability to fluoroquinolone(FQs)antibiotic of MTB,and analyze the molecular mechanism and mutation specialty of drug resistance preliminarily.Methods MTB Standard strain

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Available abstract

Objective To induct Mycobacterium tuberculosis(MTB)resistance with ofloxacin(Ofx)of stepwise increasing concentration in vitro,investigate stability to fluoroquinolone(FQs)antibiotic of MTB,and analyze the molecular mechanism and mutation specialty of drug resistance preliminarily.Methods MTB Standard strain

Key concepts: Ofloxacin, Mycobacterium tuberculosis, Microbiology, In vitro, Tuberculosis, Drug resistance, Antibiotics, Chemistry

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