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[Antigenic heterogeneity of influenza virus B neuraminidases].

E. V. Molibog, L Ia Zakstel'skaia, M A Iakhno, S. F. Shenderovich

Abstract

Antigenic relationships among neuraminidases of influenza B viruses isolated in 1940-1980 were studied by means of the neuraminidase activity inhibition test using hypoimmune sera from rats and roosters. Cross-reactions between influenza B virus enzymes showed their antigenic heterogeneity. The results permit conclusion that among influenza B virus strains both the drift and shift variants may be distinguished by the antigenic composition of the neuraminidase component.

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Available abstract

Key concepts: Neuraminidase, Antigenic shift, Antigenic drift, Sialidase, Antigen, Virology, H5N1 genetic structure, Virus