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Cladribine as monotherapy or combined with dexamethasone and idarubicin or mitoxantrone in previously treated patients with low-grade lymphoid malignancies.

Tadeusz Robak, Joanna Góra‐Tybor, Krzysztof Chojnowski

Open publisher page 6 citations

Abstract

We compared efficiency and toxicity of cladribine (2-CdA) in monotherapy and in combination with dexamethasone and mitoxantrone (CMD) or idarubicin (CID) in pretreated patients with low grade NHL. We have shown that 2-CdA has significant activity in this disease but the addition of dexamethasone and anthracyclines may not be of advantage compared to 2-CdA alone.

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What this paper is about

We compared efficiency and toxicity of cladribine (2-CdA) in monotherapy and in combination with dexamethasone and mitoxantrone (CMD) or idarubicin (CID) in pretreated patients with low grade NHL. We have shown that 2-CdA has significant activity in this disease but the addition of dexamethasone and anthracyclines may not be of advantage compared to 2-CdA alone.

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OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We compared efficiency and toxicity of cladribine (2-CdA) in monotherapy and in combination with dexamethasone and mitoxantrone (CMD) or idarubicin (CID) in pretreated patients with low grade NHL. We have shown that 2-CdA has significant activity in this disease but the addition of dexamethasone and anthracyclines may not be of advantage compared to 2-CdA alone.

Key concepts: Idarubicin, Mitoxantrone, Cladribine, Dexamethasone, Medicine, Internal medicine, Toxicity, Pharmacology

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Cladribine as monotherapy or combined with dexamethasone and idarubicin or mitoxantrone in previously treated patients with low-grade lymphoid malignancies. — Research Paper | ScholarLens