Therapy with avermectines and diazinon of psoroptic mange in sheep from Transylvania, Romania

In a study of three acaricides, doramectin (Dectomax ®, Pfizer) used at a single dose of 300 μg/kg b.w. given intramuscularly showed a high efficacy (95%) against Psoroptes ovis, in naturally infected sheep. All doramectin treated animals were clinically normal and all skin scrapings were negative for mites 50 days after treatment. At the end of experiment (70 days) only 5% of the animals showed skin lesions and a low infestation score (1+), compared to 10% for ivermectin (Romavermectine ® , Romvac Company S.A. Bucharest) and 20% for diazinon (Scabizol ®, Romvac Company S.A. Bucharest). The three treatment groups were continually in contact with infested sheep during the study.