2016•HaematologicaOpen access

Using zebrafish to model erythroid lineage toxicity and regeneration

Anna Lenard, Elisa Alghisi, Hamina Daff, Massimiliano Donzelli, Connor McGinnis, Claudia Lengerke

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Abstract

The zebrafish is a vertebrate model organism widely used to study developmental and malignant hematopoiesis. All major mammalian blood cell lineages are present in zebrafish, and many genes and pathways involved in vertebrate hematopoiesis are conserved between fish and mammals.[1][1]–[3][2] The

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What this paper is about

The zebrafish is a vertebrate model organism widely used to study developmental and malignant hematopoiesis. All major mammalian blood cell lineages are present in zebrafish, and many genes and pathways involved in vertebrate hematopoiesis are conserved between fish and mammals.[1][1]–[3][2] The

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Available abstract

The zebrafish is a vertebrate model organism widely used to study developmental and malignant hematopoiesis. All major mammalian blood cell lineages are present in zebrafish, and many genes and pathways involved in vertebrate hematopoiesis are conserved between fish and mammals.[1][1]–[3][2] The

Key concepts: Zebrafish, Vertebrate, Biology, Model organism, Lineage (genetic), Haematopoiesis, Regeneration (biology), Blood cell

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