2016•Bioorganic & Medicinal ChemistryRequires access

C-3 benzoic acid derivatives of C-3 deoxybetulinic acid and deoxybetulin as HIV-1 maturation inhibitors

Zheng Liu, Jacob J. Swidorski, Beata Nowicka-Sans, Brian Terry, Tricia Protack, Zeyu Lin, Himadri Samanta, Sharon Zhang, Zhufang Li, Dawn D. Parker, Sandhya Rahematpura, Susan Jenkins, Brett R. Beno, Mark Krystal, Nicholas A. Meanwell, Ira B. Dicker, Alicia Regueiro‐Ren

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Key concepts: Moiety, Chemistry, Pharmacophore, Benzoic acid, Stereochemistry, Potency, Cytotoxicity, In vitro