SHORT COMMUNICATION Repellency property of long chain aliphatic methyl ketones against Anopheles gambiae s.s
Ester Innocent
Abstract
Ester Innocent
Abstract
Long chain aliphatic methyl ketone series of C 7 -C 15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P<0.001) repellency response with 2-tridecanone giving comparable protection efficacy to DEET at 10% and 1% concentrations. Aliphatic methyl ketones of C 7 -C 10 had lower activity than those of C 11 -C 15. However, within this range compounds with odd carbon atoms (2-undecanone, 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms (2-decanone and 2- dodecanone). Comparable repellency activity of 2-tridecanone to DEET show that, it may save as Anopheles gambiae s.s. mosquito repellent.
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Long chain aliphatic methyl ketone series of C 7 -C 15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P<0.001) repellency response with 2-tridecanone giving comparable protection efficacy to DEET at 10% and 1% concentrations. Aliphatic methyl ketones of C 7 -C 10 had lower activity than those of C 11 -C 15. However, within this range compounds with odd carbon atoms (2-undecanone, 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms (2-decanone and 2- dodecanone). Comparable repellency activity of 2-tridecanone to DEET show that, it may save as Anopheles gambiae s.s. mosquito repellent.
Key concepts: Anopheles gambiae, DEET, Ketone, Carbon chain, Chemistry, Stereochemistry, Anopheles, Malaria